报告主题: Developing experimental models to understand why a single bacterium initiates infection in a health subject

报告人：Prof Marco R. Oggioni, University of Bologna Italy, University of Leicester United Kingdom

报告时间：5月7日（周二）9:30—11:00

报告地点：江湾校区交叉二号楼B2005会议室

报告摘要：Most people including medical personnel imagine that infections occur when we encounter many bacteria or viruses, but already in 1957 Meynell hypothesised that single bacteria are able independently to cause disease. Despite further published evidence, the uptake of this concept by the scientific community is surprisingly low. We have worked first by using animal models of infection, then by testing ex vivo perfusion of pig organs and now of human organs to investigate the events justifying such a hypothesis. The seminar will try to deliver some of this biomedical data to a non biomedical audience.

报告人简介： Prof Marco R Oggioni graduated from Medical School in Verona (Italy), did a postgraduate specialisation in Clinical Microbiology, and has then worked for twenty years as medical microbiologist in the University Hospital in Siena (Italy). Since 2013 he is professor at the University of Leicester (UK) and since 2020 also at the University of Bologna (Italy). His work on the interaction of bacteria with the host has been published in the prestigious journals Nature Communication, Nature Microbiology, Ebio Medicine and Lancet Microbe. He is currently the chief investigator of two human organ perfusion trials and the scientific lead of a further organ perfusion trial in Italy.